Expert in Api Twitter? Please!

I have been working with twitter applications, I would like to know that they recommend to avoid the suspension of the applications, because this usually happens however in many cases has not had problems, but in others yes.

When you handle many accounts (over 100) and are automated to tweet constantly, then the problems begin. I would like to know (if possible) what the exact time limits are for retweets, favs, follows, unfollows and tweets from Api.

If there is any expert in twitter api…

Expert in Api Twitter? Please!